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Queen Letizia of Spain attends the Rare Diseases Day official act at El Prado Museum on March 2, 2017 in Madrid, Spain. (Photo by Oscar Gonzalez/NurPhoto via Getty Images)

Queen Letizia of Spain attends the Rare Diseases Day official act at El Prado Museum on March 2, 2017 in Madrid, Spain. (Photo by Oscar Gonzalez/NurPhoto via Getty Images)