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MADRID, SPAIN - MARCH 02: Queen Letizia of Spain attends the Rare Diseases Day official act at El Prado Museum on March 2, 2017 in Madrid, Spain. (Photo by Fotonoticias/WireImage)

MADRID, SPAIN - MARCH 02:  Queen Letizia of Spain attends the Rare Diseases Day official act at El Prado Museum on March 2, 2017 in Madrid, Spain.  (Photo by Fotonoticias/WireImage)