MADRID, SPAIN - MARCH 05: Alfonso (L) Alonso, Queen Letizia of Spain (2ndL) and Pio Garcia-Escudero (3rd L)attend the Rare Diseases World Day ceremony at Spanish Senate on March 5, 2015 in Madrid, Spain. (Photo by Pablo Cuadra/Getty Images)
MADRID, SPAIN - MARCH 05: Alfonso (L) Alonso, Queen Letizia of Spain (2ndL) and Pio Garcia-Escudero (3rd L)attend the Rare Diseases World Day ceremony at Spanish Senate on March 5, 2015 in Madrid, Spain. (Photo by Pablo Cuadra/Getty Images)