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Advertisement for Vin Mariani wine tonic for body, brain and nerves by Mariani and Company (New York), 1899. The ad notes a gold medal award from Pope Leo XIII in recognition of benefits received from the tonic. (Photo by Jay Paull/Getty Images)

Advertisement for Vin Mariani wine tonic for body, brain and nerves by Mariani and Company (New York), 1899. The ad notes a gold medal award from Pope Leo XIII in recognition of benefits received from the tonic. (Photo by Jay Paull/Getty Images)