SAN FRANCISCO, CA - OCTOBER 25:  A medical marijuana advocate holds a sign against the U.S. Drug Enforcement Agency as he demonstrates outside of the W Hotel where U.S. President Barack Obama was holding a fundraiser on October 25, 2011 in San Francisco, California.  Hundreds of protestors from a wide variety of activist groups staged protests outside of the W Hotel where President Obama was holding a $7,500 per person fundraiser.  (Photo by Justin Sullivan/Getty Images)